Blood biomarkers recommended for diagnosing and monitoring IgG4-related disease. Considerations from the ERN ReCONNET and collaborating partners.
Jan 1, 2021·,,,,,,,,,,,,,,,,,,·
0 min read
MD PhD Luca Iaccarino
MD PhD Rosaria Talarico
MD Emanuele Bozzalla-Cassione
MD Gerd R. Burmester
MD PhD Emma L. Culver
MD Andrea Doria
MD Mikael Ebbo
PhDHyunSunJeon Md
M. Laar
M. Lanzillotta
MD Fernando Martinez-Valle
Priya Md
M. Monti
M. Nalli
MD Nicolas Schleinitz
M. Tincani
MD Emanuel Della-Torre
Prof Alexander
P. M. Hagen
Abstract
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a chronic, clinically heterogenous fibroinflammatory condition, characterised by an accumulation of IgG4 secreting plasma cells in affected tissues and associated with increased serum IgG4 concentrations. Despite a growing recognition of the disease among clinicians from different specialties worldwide, its indolent nature, lack of a single diagnostic test and ability to mimic other malignant, infective and inflammatory conditions, makes the diagnosis challenging. As treatment options evolve, biomarkers correlating with disease activity, pr…
Type
Publication
Clinical and experimental rheumatology